Adenosine 5′-triphosphate: an intracellular metabolic messenger
نویسندگان
چکیده
منابع مشابه
Intracellular compartmentalization of adenosine triphosphate.
The intracellular distribution and diffusivity of adenosine triphosphate (ATP) was studied by cryomicrodissection of individual Rana pipiens oocytes. We measured ATP concentrations in the nucleus, in animal and vegetal hemisphere cytoplasm, and in an intracellular reference phase (iRP, a microinjected gelatin "organelle") which samples diffusive ATP. Regional concentrations were not equal: nucl...
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Two major species of glucose-6-phosphate dehydrogenase (EC 1.1.1.49) differing in size, pyridine nucleotide specificity, and susceptibility to inhibition by adenosine 5'-triphosphate (ATP) were detected in extracts of Pseudomonas multivorans (which has recently been shown to be synonymous with the species Pseudomonas cepacia) ATCC 17616. The large species (molecular weight ca. 230,000) was acti...
متن کاملAdenosine 5'-triphosphate sulphurylase from Saccharomyces cerevisiae.
1. ATP sulphurylase from Saccharomyces cerevisiae was purified 140-fold by using heat treatment, DEAE-cellulose chromatography and Sepharose 6B gel filtration. 2. The enzyme was stable at -15 degrees C, optimum reaction velocity was between pH7.0 and 9.0, and the activation energy was 62kJ/mol (14.7kcal/mol). 3. The substrate was shown to be the MgATP(2-) complex, free ATP being inhibitory. 4. ...
متن کاملAntidipsogenic effects of central adenosine-5'-triphosphate.
Besides other physiological functions, adenosine-5'-triphosphate (ATP) is also a neurotransmitter that acts on purinergic receptors. In spite of the presence of purinergic receptors in forebrain areas involved with fluid-electrolyte balance, the effect of ATP on water intake has not been investigated. Therefore, we studied the effects of intracerebroventricular (icv) injections of ATP (100, 200...
متن کاملAdenosine-5'-triphosphate-induced intracellular calcium changes through gap-junctional communication in the corneal epithelium.
PURPOSE To investigate intercellular communication in the corneal epithelium, changes in the concentration of intracellular Ca(2+) ([Ca(2+)](i) ) induced by adenosine-5'-triphosphate (ATP) were analyzed. METHODS Rabbit corneal epithelia were loaded with Ca(2+) indicators and then stimulated by ATP (10 microM). [Ca(2+)](i) changes were monitored by means of conventional fluorescence and real-t...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 1998
ISSN: 0005-2728
DOI: 10.1016/s0005-2728(98)00094-2